Application of Cox Regression and Kaplan Meir Estimates in the Survival Rate of Patients
Issue:
Volume 1, Issue 2, December 2017
Pages:
29-33
Received:
10 April 2017
Accepted:
28 April 2017
Published:
3 July 2017
DOI:
10.11648/j.jb.20170102.11
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Abstract: This study aim at focusing on the survival analysis for human subjects, to compare efficacy and safety, controlled experiments which conducted as clinical trials. Sometime it is interesting to compare the survival of subjects in two or more interventions. In situations where survival is the issue then the variable of interest would be the length of time that elapses before some event to occur. In many of the situations this length of time is very long for example in cancer therapy; in such case per unit duration of time number of events such as death can be assessed. The paper is highlighting the two difference estimates in the survival distribution of patients and later explain the strengths of the two estimates when use simultaneously in estimating the survival distribution. The researchers found that, application of the two estimates; Cox regression and Kaplan Meir will result in minimum errors estimates thus producing sufficient and complete survival distribution of patients under study.
Abstract: This study aim at focusing on the survival analysis for human subjects, to compare efficacy and safety, controlled experiments which conducted as clinical trials. Sometime it is interesting to compare the survival of subjects in two or more interventions. In situations where survival is the issue then the variable of interest would be the length of...
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Studying the Optimum Conditions for the Synthesis the Derivatives of Salicylaldehyde with Halides Compounds
Issue:
Volume 1, Issue 2, December 2017
Pages:
34-39
Received:
8 April 2017
Accepted:
22 May 2017
Published:
13 July 2017
DOI:
10.11648/j.jb.20170102.12
Downloads:
Views:
Abstract: Three Dialdehydes were synthesized by the reaction of Salicylaldehyde and many Aliphatic and Aromatic Halides. The optimal condition (Catalysts, Temperature, Time of Reaction and Effect of Solvents) to get a high selective compounds and high yields have been studied. The reactions were followed by using Thin Layer Chromatography (TLC). The synthesized compounds were purified and characterized by means of High Performance Liquid Chromatography (HPLC) and spectroscopy methods: Infrared Spectra (IR), 1 H-NMR, 13C-NMR.
Abstract: Three Dialdehydes were synthesized by the reaction of Salicylaldehyde and many Aliphatic and Aromatic Halides. The optimal condition (Catalysts, Temperature, Time of Reaction and Effect of Solvents) to get a high selective compounds and high yields have been studied. The reactions were followed by using Thin Layer Chromatography (TLC). The synthesi...
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